The so-called multi-target means that in the process of intervening in life span, it insists on placing targets in multiple positions. For example, what we are doing now is that although the mode of action, level and intensity of rapamycin target mTOR in affecting human life span are very clear, and the operating environment is also very smooth, the forces that affect human life span come from many aspects. Relying solely on mTOR cannot guarantee that human life span can be extended. Therefore, expanding the target of intervention and placing it in multiple aspects of mTOR, S6K, Il-11, MAPK, ROS signaling, cell aging and calorie restriction should be a correct choice. With multiple directions and multiple paths, setting multiple intervention targets will definitely increase the chances of success;

The so-called low dose refers to supplements that interfere with life span. Since we use multiple targets, the number of supplements used is relatively much larger. High-dose supplements may be more effective, but not necessarily. When combining multiple drugs, the first thing to consider is safety. Low-dose supplement combinations will be mild and lasting, and are unlikely to inhibit or conflict with each other. Of course, this also involves the price issue we have mentioned many times. In the current supplement market, the pricing principle involves the issue of dosage. Combination supplements are time-dependent and do not require such a high dose. High-dose supplements not only increase expenses, but also reduce safety and may not improve efficacy.

The long-term problem is a highly technical problem in anti-aging and lifespan intervention operations. The effect of a supplement is completely different depending on when you take it during the day. At present, long-term does not refer to this problem. It means that if you want to implement lifespan intervention, you must be prepared to take these products continuously or intermittently for several months, years or even decades. Many people do not understand and think that the lifespan problem can be completely solved by intervening on S6K and IL-11 several times. That is completely impossible. All functions of the human body, especially the aging mechanism and lifespan mechanism, have strong genetic protection and tendency protection capabilities. This tendency inertia makes it return to its original position in a very short time after being changed by abnormal interference. Whether you are 55, 70 or 85 years old now, your behavior of intervening in lifespan can only be limited and intermittent, even if it is not continuous. Unless you give up or scientific progress discovers a more direct and simple technology to extend lifespan, such supplement intervention will eventually accompany you for the rest of your life.

This is how 2DC works. If you want to extend your life, you have to spend some time and effort.
At this point, some friends may ask, what is life extension?
There should be a standardized and strict concept for life extension. The so-called extension must have a starting point, that is, it must be clearly defined from when my life is "extended".
Based on the actual situation of various countries, human life span should basically be based on the data released by the United Nations Population Department. The life expectancy of the population in different countries is the basic life span. The life extended by a certain method should be the years after the expected life span. If it is more scientific, it should be the years after the national population life expectancy plus three years (except for malignant lesions, cancer and specific infectious diseases), which is the extended life span. For example: If the life expectancy of the population in your country is 77 years old, then after adding three, your life span will only start to be "extended" only when it exceeds 80 years old.